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J, Jamieson EC, Logan RW, McFadyen MB, Patrick WJ, Howatson AG, Cockburn F.Department of Biochemistry, Royal Hospital for Sick Children, Yorkhill NHS Trust, fatty and skinny Glasgow, fatty and skinny Scotland, UK.Abnormal fetal and infant growth have increasingly been correlated with adult onset cardiovascular disease. To date, there is little known about the lipid fatty acid profiles in infant cardiovascular tissue. Therefore, we analysed total lipid fatty acids from thoracic and abdominal aorta intima and media from 24 normally grown sudden infant death syndrome cases. Aorta fatty and skinny from small for gestational age (n = 2), failure to thrive from birth (n = 3), and premature (n = 1) infants were also examined. Dihomo-gamma-linolenic acid (C20:3n-6) and oleic acid (C18:1n-9) concentrations were significantly lower in the thoracic than in the abdominal aorta.
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