Cayman certifies that less liens strain identification

The compound features the strain identification liens

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Cayman certifies that less than 1% strain identification of the product has no deuterium incorporation (<1% d0). 10005616 12-21 N-Lignoceroyl Taurine A FAAH substrate discovered during metabolite profiling N-lignoceroyl taurine is one of several novel taurine-conjugated fatty acids discovered during mass spectrometry lipidomic analysis of brain and spinal cord from wild-type and fatty acid amide hydrolase (FAAH) knockout mice. The strain identification levels of N-lignoceroyl taurine were elevated 23-26 fold in FAAH-/- mice compared strain identification to wild-type mice, indicating that FAAH utilizes N-lignoceroyl taurine as a substrate. However, in vitro experiments with purified FAAH indicate N-lignoceroyl taurine is hydrolyzed 2,000 times more slowly by FAAH compared to oleoyl ethanolamide.

The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers liens in an intricate biochemical signal transduction cascade. 10007710 12-30 PtdIns-(3)-P1 liens (1,2-dipalmitoyl)-d62 (ammonium salt) A deuterated phosphatidylinositol for GC- or LC-MS PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions. It is intended for use as an internal standard for the quantification of PtdIns-(3)-P1 (1,2-dipalmitoyl) (ammonium salt) by GC- or LC-mass spectrometry (MS). The relative abundance of deuterium atoms incorporated into each molecule has not been determined.

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