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10005707 10-17 Tetradecyl Phosphonate A stable pan-antagonist at LPA fatty post receptors Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors with IC50 values for inhibition of LPA-induced calcium mobilization of 10 µM, fatty post 5.5 µM, and 3.1 µM, respectively. At a concentration of 10 µM, tetradecyl phosphonate activates a peroxisome proliferator-activated receptor γ reporter construct 4-fold fatty post compared to controls and partially inhibits autotaxin with an IC50 of approximately 3 µM. 10007565 10-11 15-deoxy-Δ12,14-Prostaglandin J2-biotinimide An affinity probe for 15-deoxy-Δ12,14-PGJ2 binding proteins 15-deoxy-Δ12,14-Prostaglandin J2-biotinimide (15-deoxy-Δ12,14-PGJ2-biotinimide) is an affinity probe which allows 15-deoxy-Δ12,14-PGJ2 to be detected through an interaction with the biotin ligand.
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