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What are the effects of TFA? In national library of medicine most respects the national library of medicine digestion, absorption and metabolism of TFA are the same as that of cis isomers. They are incorporated into lipids in the tissues, are present in human milk and are catabolised in the same way as the cis isomers. Selective accumulation in tissues does not occur. TFA are oxidised to provide energy. national library of medicine Although there is some evidence from in vitro and animal studies that conversion of essential fatty acids is inhibited by TFA, metabolism of essential fatty acids is unlikely to be impaired by TFA when intakes of essential fatty acids meet recommended levels. Correlations have been unscientifically drawn between the increased use of hydrogenation and the increase in coronary heart disease (CHD) and other health problems.
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