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  It should be noted that aspects of the Hu et al study have been called into question. Ockene and Nicolosi (1998) have pointed firms out some inconsistencies in data that suggest the possibility that the method of assessing either the diet or exercise may be flawed, and also the danger of drawing conclusions from a study in which there was much lower risk of coronary heart disease (27 deaths per 100,000 firms per firms year) in the group of women studied, who were all nurses, than the overall risk in the population of women in the United States (rates of death from heart disease among white women 45 to 64 years of age in the United States: 62.5 and 51.0 per 100,000 per year, respectively, in 1985 and 1989). Hegsted (1998) points out that the range of total fat intake recorded in these studies is limited and has little relevance to the protective effect of really low fat diets.
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