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However, the methodology in this work has been criticised (Sanders, 1988) and Kritchevsky (1982) concluded that TFA in hydrogenated vegetable fat when fed in amounts up to 14% of energy intake were not atherogenic; nor were partially hydrogenated fish oils (Sanders, 1988). 5. TFA can cause an increase in plasma lipoprotein (a) concentration (especially in individuals with a high starting level) which is considered by some workers in the field to be an independent risk factor for CHD. Hu et al (1997) made an epidemiological assessment drawn from data double bond in the double bond US-based Nurses' double bond Health Study. The authors prospectively studied 80,082 women who were 34 to 59 years of age and had no known coronary disease, stroke, cancer, hypercholesterolemia, or diabetes in 1980.
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