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Eicosanoids are involved in the initiation of inflammatory responses, the regulation of blood circulation and sample preparation pressure, the control of ion transport through sample preparation membranes, the modulation of synaptic transport, the sample preparation induction of blood clotting, the regulation of the sleep/wake cycle, and the control of several reproductive functions. Recently, a great deal of interest has been paid to the AA/EPA ratio. According to Dr. Sears, a lower AA/EPA ratio indicates a better balance of "good" and "bad" eicosanoids in your body. An AA/EPA ratio of 1.5 is considered to be ideal since this is the ratio found in the Japanese population having the greatest longevity and the lowest incidence of cardiovascular disease. Dietary fatty acids influence the level of cholesterol-containing lipoproteins in the serum, impacting the risk for atherosclerosis and cardiovascular disease. Saturated fatty acids increase the level of LDL in the blood serum, while monounsaturated fatty acids (MUFAs) and polyunsaturated fatty acids (PUFAs) decrease the level of LDL and increase the level of HDL.
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